Coordination & Intelligence Layer

Complex cases, finally readable.

Years of reports, specialists and unanswered questions — reconstructed into one source-linked case both sides can actually use.

Source-linked Human-reviewed Not a medical device (MDR) Swiss data residency · nDSG · GDPR

Section 02 · The four surfaces

One layer. Four points of view.

The same underlying case — rendered for patient, provider, payer and the nexus that holds them together. Each view has its own hook, its own central question, and its own dashboard.

Hook

You should not need a project manager to survive your own illness.

Central question

What is my next step — and what does my body actually say?

One calm surface across appointments, symptoms, specialties and open questions. Built for people who are exhausted, coordinating a life, a diagnosis and often a family.

Coordination load — one week

Mo
Tu
We
Th
Fr
Sa
Su

Calls, portals, insurers, referrals, prescriptions — carried by the patient.

NAVORAMy health · read & prepareAnna · P-2026-047Today · 12 Jul · Zürich
Next visit in 2 d3 tasks open1 lab pendingFlare activeConsent up to date

My case at a glance

What you already know · what to bring on Tuesday

Duration

5 y

Since 2021

Specialists met

6

No lead physician

Confirmed dx

2

ADHD · Vit D

Open tasks

3

1 overdue

Next appointment

Tue · 14 Jul · 09:30

Neurology · Dr. Keller

Inselspital · Room 4.12

  • Bring lab printout (24 Jun)Tue
  • Note flare triggers this weekOngoing
  • Send IV form to case managerOverdue

Energy — last 12 weeks

W-12This week

Self-report + wearable · flare episodes marked

Symptom duration

Fatigue · 22 mo92%
Concentration · 18 mo75%
Sleep · 12 mo50%
Joint pain · 6 mo25%

Diagnoses

Confirmed

ADHD (late dx)100%
Vit D deficiency100%

Suspected — under review

ME/CFS78%
Iron dysregulation62%
Neuroimmune48%

You decide what is shared and with whom. Every value shown here comes from your own records — source-linked and reversible.

Missing from work · school · life

One patient. CHF 300,000+ absorbed by the system.A life put on hold.

ME/CFS, Long COVID, autoimmune, endocrine, neuro-immune — the invisible chronic multisystemic diseases. Patients disappear from work, from school, from the people they love. The system keeps paying. Nobody is coordinating. Nobody is connecting the dots.

2.5 yrs

Missing from the workforce

CHF 300k+

Direct + indirect system cost

5+

Specialties involved, no owner

0

Systems that talk to each other

MVP · Expert Validation Stage

Complex cases don't need another summary. They need reconstruction.

NAVORA reconstructs fragmented medical histories into source-referenced, reviewable clinical case logic — with a timeline, gaps, contradictions and a specialty-directed briefing.

Source-linked

Every statement stays linked to its document, date and review status.

Human-reviewed

No autonomous diagnosis, no treatment recommendation. Clinical review stays central.

Phase 0 ready

A PDF upload is enough to validate usefulness before integration.

A single case · fully documented

High-performing professional.
Missing for 2.5 years.

Last total compensation of CHF 147,000 in a demanding banking role. Then a chronic multisystemic disease. What follows is what the system spent — and what the patient permanently lost.

Employer — salary continuation (12 mo, 100%) CHF 115,000
Daily-allowance insurer (12 mo, 90%) CHF 103,500
Direct healthcare costs CHF 60,000
IV early detection + 10-month coaching · est.CHF 25,000
Team absorbing workload (soft cost) · est.CHF 40,000

Total system cost — one patient

CHF ~343,500

What the patient lost

Irreversible. Not on any balance sheet.

  • Career trajectory · terminated
  • Social environment · lost
  • Relationship · lost
  • Near-total isolation
  • Coverage gap between IV, KTV, RAV, employer
  • Still coordinating everything — for self and for a child with ME/CFS

And this is one case

Multiplied across ME/CFS, Long COVID and the invisible chronic diseases: a silent, structural failure the system pays for every day — while patients disappear from it entirely.

The structural problem

The data exists. The clinical orientation does not.

Complex cases rarely fail for lack of information. They fail because findings, lab values, reports, symptoms and course never become readable as one connected clinical trajectory.

CHF 90B+

Annual Swiss health expenditure (~12% GDP)

~10%

Ambulatory physician connectivity

<1%

EPD adoption in the population

Context figures on the care system — not NAVORA outcomes. Sources: Swiss federal health statistics; DigiSanté / Obsan.

Visible burden

  • Consultations & diagnostics
  • Medication & therapies
  • Hospitalisations
  • Disability insurance & social support

Invisible burden

  • Repeated case reconstruction
  • Care work carried by relatives
  • Delayed resolution of open questions
  • Avoidable cases becoming chronic

Handover loss

Context breaks at every change of specialty. Each handover reduces the case back to fragments.

Repeated work

The case is explained from scratch again and again. Patients and clinicians reconstruct the same story repeatedly.

Synthesis gap

More data does not automatically create understanding. Without a layer of meaning, data stays technically available but clinically hard to use.

Synthesis gap

Connectivity is not clinical usability.

Interoperability moves data. NAVORA focuses on what is still missing afterwards: a reviewable layer of meaning across documents, timelines, specialties and open questions.

Data & systems

  • EHR / HIS
  • Documents
  • Devices
  • Imaging
  • Patient apps

NAVORA layer

  • Source-referenced
  • Longitudinal
  • Human-controlled
  • Reviewable case view

Clinician

  • Coherent case view
  • Ready for decision context
  • No autonomous output
  1. 01

    Every appointment starts from zero. When did it begin? What was ruled out? Which values were abnormal?

  2. 02

    Systems document episodes. Diagnoses, services and encounters are stored — but never modelled as a trajectory.

  3. 03

    Signals emerge over time. Connections, comorbidities and loss of function only become visible longitudinally.

Developed for

Built for the settings where the case is bigger than one visit.

NAVORA is designed around Swiss ambulatory and interdisciplinary care — where a single case can touch 5–15 institutions over years, and every specialty inherits a fragment instead of a trajectory.

Specialist practices

Rheumatology · Neurology · Internal medicine

Practices carrying complex chronic cases across years of reports, labs and specialist letters — where every consult starts by re-reading the file.

Chronic multi-encounter cases8-min consult prepReferral-ready briefings
Clinics & departments

Interdisciplinary case review

Tumor boards, ME/CFS clinics, long-COVID units and rare-disease programs that need a source-linked case reconstruction before the board meets.

Tumor boardsCase conferencesHandover across specialties
Care networks & payers

IV · KTV · employer coordination

Coordination teams reconciling salary continuation, IV coaching, disability, RTW and case management with a single reviewable clinical trajectory.

IV / disabilityCase managementReturn-to-work
Patient companion

Patients & caregivers

A read-mode surface for patients and caregivers — timeline, open questions and prepared consultation packages, without diagnostic claims.

Read-modeConsent-nativePrepared consults

Product principle

Not a chatbot over medical PDFs. A verifiable pipeline.

NAVORA turns documents not into a one-off summary, but into structured clinical objects, a timeline, source tags, review status and reusable case logic.

  1. 1

    Input

    PDFs, reports, labs, notes

  2. 2

    Ingestion

    Extraction, OCR/NLP, date logic

  3. 3

    Structuring

    Clinical objects, not free text

  4. 4

    Timeline

    Trajectory, not an episode list

  5. 5

    Gap Layer

    Gaps, contradictions, open questions

  6. 6

    Briefing

    Reviewable, specialty-directed

Module

Core

Structured case foundation. Source references, clinical objects, review status, auditability, role-based access.

Module

Klio

Clinical story engine. Readable case narratives, consultation preparation, specialty-directed briefings.

Module

Tractus

Longitudinal pathway intelligence. Timeline, turning points, documentation gaps and trajectory views over time.

Product · Focus modules for Physicians & Patients

One pipeline. Three modules. One reviewable case view.

Core, Klio and Tractus are the first release focus — built for physicians and patients working through complex, multi-year cases. Every output stays linked to the source document, the reviewer and the moment in the trajectory.

Module

Core

Structured case foundation

Turns unstructured reports, PDFs and lab exports into source-referenced clinical objects with review status, roles and audit trail.

Open Core
  • Document → object extraction (OCR + medical NLP)
  • Source tags: document, section, date, author, confidence
  • Role-based access · audit trail · review states
  • Consent-native data model (nDSG / GDPR)
Module

Klio

Clinical story engine

Composes readable, specialty-directed case narratives and consultation briefings — always linked back to source objects.

Open Klio
  • Consultation briefings per specialty
  • Open questions & contradictions surfaced
  • Patient-readable summary layer
  • No autonomous diagnosis · reviewable output only
Module

Tractus

Longitudinal pathway intelligence

Reconstructs the case as a trajectory across years, specialties and institutions — highlighting turning points and documentation gaps.

Open Tractus
  • Multi-encounter timeline reconstruction
  • Turning points, plateaus & regressions
  • Documentation gap map
  • Trajectory export for tumor boards & case reviews

Product · Comparison

Core, Klio, Tractus — at a glance.

Three modules, one pipeline. Each answers a different question about the same case — and each output stays linked back to Core's source objects. Each row highlights the module best positioned to answer that dimension, with a direct link into its page.

DimensionCoreStructured case foundationKlioClinical story engineTractusLongitudinal pathway intelligence
Purpose

Everything downstream depends on a source-referenced object model.

Structure, provenance & source logicClear, readable case storyTrajectory across time
Input

Core is the only module that ingests raw documents.

PDFs, reports, lab exports, lettersCore objects + specialty contextCore objects across encounters & years
Primary output

Reviewable briefing is what a clinician opens before a consultation.

Source-referenced clinical objectsSpecialty-directed briefing & open questionsTimeline with turning points & gaps
Distinguishes

The finding/diagnosis/hypothesis split is Core's contract.

Finding · observation · diagnosis · hypothesisWhat is known vs. what is still openOnset, plateau, regression, trigger candidates
Answers

Klio answers the question a clinician actually asks at t=0.

Where does this value come from?What is this case about — right now?How did we get here, and when did it shift?
Primary user

Physician-in-consultation is the first release focus.

Every downstream module + reviewerPhysician preparing a consultationPhysician + patient reviewing the arc
Time horizon

Only Tractus reconstructs the multi-year arc.

Per documentPer encounter / questionMulti-year, multi-institution
Not

Non-generative provenance is the strongest guardrail.

Not a text generatorNot an autonomous diagnosisNot a predictive model

Perspective · Beyond the initial focus

Physicians and patients first. The rest is the roadmap.

Core, Klio and Tractus ship first — because that is where the orientation gap is sharpest. The modules below are the deliberate next arc: continuity, pattern, cohort and coordination layers built on the same source-referenced foundation.

Perspective

Patient Companion

Structured self-observation

Helps patients capture symptoms and observations in an ordered way — translating everyday experience into medically usable structure.

  • Guided symptom & context capture
  • Less explanation burden before appointments
  • Feeds directly into Core as reviewable objects
Perspective

Continuum

Care between appointments

Connects clinic visits to daily life — flares, stabilisation, exertion limits and warning signals become visible instead of lost between encounters.

  • Flare & stabilisation view
  • Exertion & warning-signal tracking
  • Continuous course control, not point-in-time snapshots
Perspective

Pattern Intelligence

Testable patterns, not diagnoses

Surfaces recurring relationships between exertion, symptoms, labs, sleep or medication. It does not diagnose — it makes patterns visible for review.

  • Cross-signal correlations
  • Reviewable hypotheses, never autonomous claims
  • Every pattern traceable to source data
Perspective

Cohort Intelligence

Anonymised case comparison

Compares similar cases in a privacy-preserving way. Over time this reveals care patterns, risks and treatment effects relevant to research and quality.

  • Anonymised, consent-based cohorts
  • Care pattern & outcome signals
  • System-level learning loop
Perspective

Nexus

Structured cross-actor coordination

Structures collaboration across all involved parties — showing responsibilities, open questions and next steps to reduce coordination chaos for patients and families.

  • Responsibilities & handoffs mapped
  • Open questions tracked to closure
  • Shared next-step view across care team
Perspective

Assist

From complexity to concrete tasks

Translates complex situations into concrete everyday tasks — documents, appointments, applications, questions and relief steps that patients today coordinate alone.

  • Task generation from case state
  • Application & document guidance
  • Practical relief where the system leaves gaps

Market position

Healthcare AI is growing. Continuity is still missing.

Scribes document conversations. EHR/HIS AI optimises one system. Diagnostic AI detects findings. Research platforms analyse cohorts. NAVORA reconstructs the complex case across time, sources and specialties.

Scribes document the visit.

NAVORA reconstructs the case.

EHR AI improves one system.

NAVORA connects what no single system contains.

Diagnostic AI detects findings.

NAVORA makes the trajectory reviewable.

Research platforms analyse cohorts.

NAVORA prepares the next clinical review.

Competitive edge · AWS landscape analysis

The only layer built for source-referenced multi-encounter case reconstruction.

The AWS competitive landscape confirms it: scribes, EHR AI, diagnostic AI and research platforms each solve one slice. None reconstruct the complex ambulatory case across years, specialties and institutions.

CategoryReference playersTheir focusGap NAVORA fills
Ambient scribesAbridge · Nuance DAX · CortiReal-time visit documentation One encounter — no multi-year reconstruction
EHR-embedded AIEpic · Cerner · DedalusOptimises within one system Blind to documents outside the EHR
Diagnostic AIAidoc · Regard · PathAIFindings within one modality No cross-specialty trajectory
Research platformsFlatiron · TempusCohort-level analysis Not built for the next consultation

Source-referenced synthesis

Every synthesised statement stays linked to the exact document, section and date.

Multi-encounter reconstruction

Years of reports, labs and letters composed into one reviewable trajectory.

Human-in-the-loop by design

V0 outputs orientation only — never autonomous diagnosis or treatment.

Technical foundation

Built on a controlled, EU-hosted AWS healthcare stack.

NAVORA runs on AWS's healthcare-eligible services in the EU, combined with a Swiss hosting layer for identifying data. LLM calls are wrapped in guardrails and audit trail; nothing leaves the controlled boundary without a source tag.

AWS HealthLake

FHIR R4 clinical data lake — EU (Frankfurt) region.

Amazon Comprehend Medical

HIPAA-eligible medical NLP for entity, RxNorm and ICD-10 extraction.

Amazon Bedrock AgentCore

Controlled LLM orchestration with guardrails and audit trail.

AWS Nitro & KMS

Isolated compute enclaves, customer-managed keys, envelope encryption.

EU / CH

Data residency for clinical content

AES-256

Encryption at rest & in transit (TLS 1.3)

Zero-retention

LLM prompts and outputs, no training on client data

Trust architecture

Clinical trust is not a claim. It is product architecture.

NAVORA V0 is deliberately narrow: case structuring, source linking, timeline, gap marking and a review flow. No autonomous diagnosis. No treatment recommendation. No triage.

01

Every statement has a source.

Document, section, date, author/institution, extraction confidence and review status stay visible.

02

Uncertainty remains visible.

Gaps and contradictions are not smoothed over, but marked as reviewable orientation.

03

Human judgement stays central.

The software supports the decision context. Responsibility stays with the physician.

04

Consent-native by design.

Data minimisation, purpose limitation, pseudonymisation, visible consent logic — as baseline.

05

Role-based access.

Patient, physician, caregiver and admin receive different rights, permissions and audit trails.

06

Regulatory boundary first.

V0 avoids decision-support wording and stays limited to reviewable orientation.

From the product — ingestion path

NAVORA starts with a drag & drop. Structured HL7 FHIR and HIN connectivity are added only when a pilot has proven the value is real.

Ingestion — from PDF to FHIR
Swiss residency · pseudonymised

Phase 0 · today

Drag & drop

Drop PDFs / images or click to upload
Rheumatology_2024-03.pdf
1.2 MB
MRI_cervical_2023.pdf
4.8 MB

No integration required. The patient or practice provides source documents.

Core

Structured objects

Diagnoses7
Findings44
Timeline entries126
Open questions5

Every object is source-linked — document, section, date, author.

Phase 1 · pilot integration

Secure API · HL7 FHIR

POST /cases/{id}/documentsready
GET /cases/{id}/timelineready
FHIR Bundle exportready
HIN · EPD connectorplanned

When the pilot demands it — never before real usefulness is proven.

Data protection & security

Clinical trust starts with the Swiss compliance boundary.

NAVORA is designed against Swiss and European healthcare requirements from day one: identity via HIN and GLN, clinical hosting in CH / EU, and a regulatory posture that keeps V0 firmly outside MDR-regulated decision support.

Swiss nDSG & EU GDPR aligned

Purpose limitation, data minimisation, right of access and deletion are enforced at the data model — not the interface.

Data residency in CH & EU

Identifying data hosted in a Swiss ISO 27001 Tier III data centre; clinical processing in AWS EU regions.

HIN & GLN identity

Physician authentication via HIN; providers identified by GLN to align with the Swiss e-health ecosystem.

Customer-managed encryption

AES-256 at rest, TLS 1.3 in transit, envelope encryption with customer-managed keys via AWS KMS.

Full audit trail

Every access, extraction and review action is logged, timestamped and attributable to a role.

Consent-native by design

Patient consent is a first-class object — scoped by purpose, revocable, and visible to every role.

Swiss nDSG (revDSG)EU GDPRISO 27001 hostingHIN-readyGLN identityAWS HIPAA-eligible servicesNo autonomous diagnosisMDR — not a medical device (V0)

Section 03 · Validation KPIs

How we measure the pilot.

Ten metrics grouped into four layers. Each KPI carries its collection method and target corridor — the backbone of Phase 0 with our pilot partners.

Clinical Utility

3 KPIs

Value at the case level — measured from the clinician's perspective.

Time-to-understand-case

Median seconds to first workable case hypothesis

Method
In-app timer, baseline vs. NAVORA-assisted
Target
−40% vs. baseline

Review time per case

Average handling time per case

Method
Session tracking + self-report
Target
−25% with no loss of quality

Clinician-rated usefulness

Likert 1–7 after each case

Method
In-app micro-survey (2 questions)
Target
≥ 5.5 median

Evidence Quality

3 KPIs

Does NAVORA back up what it shows — and catch what is missing?

Source verification success

% of statements with a traceable, valid source

Method
Sample audit by a clinical review panel
Target
≥ 95%

Missed-gap detection

% of clinically relevant gaps correctly flagged

Method
Retrospective comparison against gold-standard cases
Target
≥ 80% recall

Contradictions identified

Average confirmed contradictions per 10 cases

Method
Reviewer adjudication
Target
> baseline (manual review)

Commercial Signal

3 KPIs

Early indicators of willingness to pay and to continue.

Willingness to use again

% of pilot users who voluntarily start another case

Method
Behavioural tracking over 4 weeks
Target
≥ 70%

Willingness to pay

Van Westendorp price-acceptance range

Method
Structured interview at pilot close
Target
Optimal price point definable

Pilot continuation intent

% of sites signing an LOI for Phase 1

Method
Written letter of intent
Target
≥ 60% of pilot sites

Patient Layer

1 KPI

Clarity for patients and caregivers (optional read-mode).

Patient / caregiver perceived clarity

Comprehension score 1–5 after read-mode

Method
Post-consultation survey
Target
≥ 4.0 median

Phase 0 validation

Usefulness before automation. Value before integration.

The first validation needs no deep EHR, HIS or FHIR integration. A PDF upload is enough to test whether NAVORA makes complex cases faster to understand, easier to review and more clinically connectable.

84

Day validation window

3

Clinical settings

CHF 1,500

MRR target

V0

Manual review / wizard-of-oz

Binary go / no-go criteria — targets for validation, not results achieved.

  1. 1

    Upload / Export

    Patient or practice provides PDFs, reports and selected longitudinal records.

  2. 2

    Manual + assisted structuring

    Documents become clinical objects, timeline entries, source tags and open questions.

  3. 3

    Expert review

    Clinicians evaluate usefulness, correctness, understandability and review effort.

  4. 4

    Pilot decision

    Continue only if real cases create measurable willingness to keep using NAVORA.

Phase 0 · Reference

These KPIs are the backbone of Phase 0.

The validation KPIs are a fixed part of the pilot agreement with our first clinical partners. Results are reviewed together at the end of each 4-week cycle.

4-week cycles, quantitative + qualitative
Clinical review panel for gap & source KPIs
No autonomous diagnosis or treatment claim

For validation partners

Start where complexity is undeniable.

NAVORA is looking for clinical sparring partners, specialists and healthcare operators who will critically pressure-test complex longitudinal cases, MVP limits, regulatory edges and pilot logic.

For clinical, technical, research or ecosystem conversations. We respond to thoughtful, relevant introductions.

Primary interest

  • Clinical validation partnership
  • Technical / architecture partnership
  • Research collaboration
  • Mentoring / advisory
  • Ecosystem introduction
Response window · 5 working days